Jesús A Izaguirre


Office:326C Cushing Hall
University Voice/Text:(574) 631-7454
Email:izaguirr@nd.edu

HomePage

Research Interests

Computational molecular biophysics, focusing in problems such as protein folding kinetics and protein allostery networks, ribosomal translocation, and Computational systems biology, focusing in problems related to protein-protein interaction networks, such as inference and validation of interactions, integration of various network information using Bayesian and graph theoretical approaches.

Educational Background and Employment

1999-PhD in Computer Science, University of Illinois at Urbana-Champaign
1996-MS in Computer Science, Specialization in Computational Science and Engineering, University of Illinois at Urbana-Champaign
1991-BS in Electronic Systems Engineering, Tecnológico de Monterrey, Mexico
2005-present Associate Professor (with tenure), Dept. of Computer Science and Engineering, University of Notre Dame
2006-2008 Visiting Professor, Institute for Computational and Mathematical Engineering, Stanford University
1999-2005 Assistant Professsor, Dept. of Computer Science and Engineering, Univ. of Notre Dame

Selected Publications

Santanu Chatterjee, Christopher R. Sweet, and Jesús A. Izaguirre.
String Method with Collective Variables from Instantaneous Normal Modes.
Submitted, 2011. PDF
F. Morcos, S. Chatterjee, C. L. McClendon, P.R. Brenner, R. Lopez-Rendon, J. Zintsmaster, M. Ercsey-Ravasz, C. R. Sweet, M.P. Jacobson, J.W. Peng, J. A. Izaguirre.
Modeling conformational ensembles of slow functional motions in Pin1-WW.
PLoS Comput Biol 6(12): e1001015. doi:10.1371/journal.pcbi.1001015
Faruck Morcos, Marcin Sikora, Mark Alber, Dale Kaiser and Jesus A. Izaguirre.
Belief Propagation Estimation of Protein and Domain Interactions using the Sum-Product Algorithm.
IEEE Transactions on Information Theory, Special Issue on Information Theory in Molecular Biology and Neuroscience. Vol. 56, No. 2, Pages 742-755, (Feb 2010).
Jesús A. Izaguirre, Chris R. Sweet, and Vijay S. Pande.
Multiscale dynamics of macromolecules using Normal Mode Langevin.
Pac Symp Biocomput. 15:240-51, (2010)
Faruck Morcos, Marcin Sikora, Mark Alber, Dale Kaiser, and Jesús A. Izaguirre.
Estimation of Protein and Domain Interactions in the Switching Motility System of Myxococcus xanthus.
Pac Symp Biocomput. 15:157-65, (2010).
Kanaan SP, Huang C, Wuchty S, Chen DZ, Izaguirre JA.
Inferring protein-protein interactions from multiple protein domain combinations.
Methods Mol Biol. 541:43-59, (2009).
Faruck Morcos, Charles Lamanna, Nitesh V. Chawla, and Jesús A. Izaguirre.
Determination of Specificity Residues in Two Component Systems using Graphlets.
Proc. 2009 International Conference on Bioinformatics & Computational Biology BIOCOMP' 09.
C.R. Sweet, P. Petrone, V.S. Pande, J.A. Izaguirre.
Normal Mode Partitioning of Langevin Dynamics for Biomolecules.
J. Chem. Phys. 128:145101, 2008.
Faruck Morcos, Charles Lamanna, Marcin Sikora, and Jesus Izaguirre.
Cytoprophet: A Cytoscape plug-in for protein and domain interaction networks inference.
Bioinformatics, 19:2265-2266, 2008.
Chengbang Huang, Faruck Morcos, Simon P. Kanaan, Stefan Wuchty, Danny Z. Chen, and Jesús A. Izaguirre.
Predicting Protein-Protein Interactions from Protein Domains Using a Set Cover Approach.
IEEE/ACM Transactions on Computational Biology and Bioinformatics, Vol. 4, pp. 1-10, 2007.